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Cdc7 inhibitor 7c
CAS No. 1330781-04-8
Cdc7 inhibitor 7c( Cdc7-IN-7c | Cdc7 IN 7c | Cdc7IN7c | Cdc7 inhibitor 7c )
Catalog No. M11315 CAS No. 1330781-04-8
A highly potent, selective and time-dependent Cdc7 kinase inhibitor with IC50 of 0.7 nM with slow dissociation property, with 200-fold and >14,000-fold selectivity over CDK2 and ROCK1, respectively.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 745 | Get Quote |
|
| 10MG | 1017 | Get Quote |
|
| 25MG | 1431 | Get Quote |
|
| 50MG | 1782 | Get Quote |
|
| 100MG | 2250 | Get Quote |
|
| 500MG | 4410 | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameCdc7 inhibitor 7c
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NoteResearch use only, not for human use.
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Brief DescriptionA highly potent, selective and time-dependent Cdc7 kinase inhibitor with IC50 of 0.7 nM with slow dissociation property, with 200-fold and >14,000-fold selectivity over CDK2 and ROCK1, respectively.
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DescriptionA highly potent, selective and time-dependent Cdc7 kinase inhibitor with IC50 of 0.7 nM with slow dissociation property, with 200-fold and >14,000-fold selectivity over CDK2 and ROCK1, respectively; exhibits significant time-dependent Cdc7 inhibition with slow dissociation kinetics, cellular pharmacodynamic (PD) effects, and COLO205 growth inhibition.
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In Vitro——
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In Vivo——
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SynonymsCdc7-IN-7c | Cdc7 IN 7c | Cdc7IN7c | Cdc7 inhibitor 7c
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PathwayAngiogenesis
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TargetCDK
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RecptorCDK
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Research AreaCancer
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Indication——
Chemical Information
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CAS Number1330781-04-8
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Formula Weight315.395
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Molecular FormulaC15H17N5OS
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Purity>98% (HPLC)
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Solubility——
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SMILESO=C1C2=C(C=C(C3=CNN=C3C)S2)N=C(CN4CCCC4)N1
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Chemical Name6-(3-methyl-1H-pyrazol-4-yl)-2-(pyrrolidin-1-ylmethyl)thieno[3,2-d]pyrimidin-4(3H)-one
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Kurasawa O, et al. Bioorg Med Chem. 2017 Jul 15;25(14):3658-3670.
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